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142678-92-0

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142678-92-0 Usage

General Description

(1R,2S)-2-Amino-2,3-dihydro-1H-inden-1-ol is a chiral compound with a chemical formula C9H11NO. It is also known as (R,S)-2-amino-2,3-dihydro-1H-inden-1-ol and is a key intermediate used in the synthesis of pharmaceutical compounds and organic molecules. This chemical is an amino alcohol, containing a hydroxyl group and an amine group, and it is mainly used as a building block in the production of various chiral drugs and chemical compounds. Its stereochemistry, particularly its (1R,2S) configuration, makes it a valuable molecule in drug synthesis and medicinal chemistry, with potential applications in the treatment of various diseases and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 142678-92-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,6,7 and 8 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 142678-92:
(8*1)+(7*4)+(6*2)+(5*6)+(4*7)+(3*8)+(2*9)+(1*2)=150
150 % 10 = 0
So 142678-92-0 is a valid CAS Registry Number.

142678-92-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R,2R)-trans-2-amino-1-indanol

1.2 Other means of identification

Product number -
Other names 2-Amino-indanol-(1)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:142678-92-0 SDS

142678-92-0Relevant articles and documents

Cyclic alpha-dehydroamino ketones, chiral cyclic alpha-amino ketone and preparation method thereof

-

, (2017/04/20)

The invention provides cyclic alpha-dehydroamino ketones, chiral cyclic alpha-amino ketone and a preparation method of the chiral cyclic alpha-amino ketone. The preparation method comprises the following steps: enabling the cyclic alpha-dehydroamino ketones as shown in a general formula (1) to react in an organic solvent at a hydrogen atmosphere under the catalytic effect of diphosphine-rhodium complex to obtain the chiral cyclic alpha-amino ketone as shown in a general formula (2). The preparation method adopts an asymmetric catalytic hydrogenation, is simple and effective in process, and is suitable for industrial large-scale production. The product, chiral amino ketone, prepared according to the method can be further derived into chiral amino ketone alcohol ligand and chiral amino medicine intermediate, thus having wide application in the industry.

Cyclic trans-β-amino alcohols: Preparation and enzymatic kinetic resolution

Rouf, Abdul,Gupta, Pankaj,Aga, Mushtaq A.,Kumar, Brijesh,Parshad, Rajinder,Taneja, Subhash C.

, p. 2134 - 2143 (2012/05/04)

Enantioenriched cyclic β-amino alcohols, trans-2-aminocyclohexanols (ee, >99%), trans-2-aminocyclopentanols (ee, >99%), trans-1-amino-2- indanols (ee, >99%) and trans-2-amino-1-indanols (ee, ~98%) were prepared in high yields via an Arthrobacter sp. Lipase/PLAP catalyzed kinetic resolution of racemic phthalimido acetates. The addition of toluene as a co-solvent dramatically improved the hydrolysis and enantioselectivity, whereas for indanols, substrate immobilization on Celite improved the efficacy of the kinetic resolution.

Efficient synthesis of a chiral mediator

-

, (2008/06/13)

An efficient method for the quantitative preparation and isolation of a compound of formula I STR1 or its enantiomer, a chiral mediator used in enantioselective synthesis.

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