1426927-58-3Relevant articles and documents
Highly enantioselective synthesis of multifunctionalized dihydrofurans by copper-catalyzed asymmetric [4 + 1] cycloadditions of α-benzylidene- β-ketoester with diazo compound
Zhou, Jiao-Long,Wang, Li-Jia,Xu, Hao,Sun, Xiu-Li,Tang, Yong
, p. 685 - 688 (2013)
Highly efficient synthesis of chiral tetrasubstituted 2,3-dihydrofuran derivatives has been realized by Cu-catalyzed asymmetric [4 + 1] cycloadditions of α-benzylidene-β-ketoester with a diazo compound. Following this methodology, a series of optically active multifunctionalized dihydrofurans were prepared in high yield with up to 96% ee and 99/1 dr.
