1426955-89-6

Basic information

• Product Name: (R)-4-(1-amino-2-methylpropyl)benzonitrile hydrochloride
• Synonyms: (R)-4-(1-amino-2-methylpropyl)benzonitrile hydrochloride
• CAS NO: 1426955-89-6
• Molecular Weight: 210.706
• Mol File: 1426955-89-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-(1-amino-2-methylpropyl)benzonitrile hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-(1-amino-2-methylpropyl)benzonitrile hydrochloride(1426955-89-6)
• EPA Substance Registry System: (R)-4-(1-amino-2-methylpropyl)benzonitrile hydrochloride(1426955-89-6)

Safety Data

• Hazardous Substances Data: 1426955-89-6(Hazardous Substances Data)

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 935263-24-4 (R)-(-)-N-(4-cyanobenzylidene)-2-methylpropane-2-sulfinamide 
• 1426955-77-2 (R_S,R)-N-(1-(4-cyanophenyl)-2-methylpropyl)-2-methylpropane-2-sulfinamide 

Relevant articles and documents

Intermolecular alkyl radical additions to enantiopure N-tert-butanesulfinyl aldimines

The sulfinyl group in (R)-N-tert-butanesulfinyl aldimines provides efficient control of the stereoselectivity in the intermolecular reactions with alkyl radicals. The methodology is applicable to aryl, heteroaryl, benzyl, and alkynyl imines, even those containing CN, CO2Me, COR, and OH groups. The best results are attained with hindered radicals (tertiary and secondary ones) without C=N bond reduction. This reaction complements the well-established organometallic additions to N-sulfinyl aldimines to obtain enantiomerically pure functionalized α-branched primary amines.