1427002-67-2

Upstream product

• 326-06-7 1-Phenyl-4,4,4-trifluorobutane-1,3-dione 
• 934-32-7 1H-benzimidazol-2-amine 
• 1427002-64-9 C₁₇H₁₁F₃N₄O₂ 
• 50996-16-2 5,6-diamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride 

Downstream Products

• 1427002-76-3 C₂₅H₁₆F₆N₈O₃ 

Relevant academic research and scientific papers

Synthesis of some novel 7-(1H-benzimidazol-2-ylazo)-1,3- -dimethyl-6,8-disubstituted-1H-pyrimido[4,5-b] [1,4]diazepine-2,4-diones as potential anti-anxiety agents

An efficient and mild method for the synthesis of some novel 7-(1H- -benzimidazol-2-ylazo)-1,3-dimethyl-6,8-disubstituted-1H-pyrimido[4,5-b]- [1,4]diazepine-2,4-diones in water has been developed. This method is a good option to obtain the title compounds in quantitative yields in a simple and inexpensive manner. Further, the NH of the title compounds was replaced by various substituents in an ionic liquid, [bmim]PF6, a recyclable and environmentally benign solvent. The synthesized compounds were characterized by analytical and spectral (IR, 1H-NMR, 13C-NMR and FAB mass) data and have been screened for their anti-anxiety activity in mice.