1427016-81-6Relevant articles and documents
General synthesis of sugar-derived azepane nitrones: Precursors of azepane iminosugars
Zhao, Wen-Bo,Nakagawa, Shinpei,Kato, Atsushi,Adachi, Isao,Jia, Yue-Mei,Hu, Xiang-Guo,Fleet, George W. J.,Wilson, Francis X.,Horne, Graeme,Yoshihara, Akihide,Izumori, Ken,Yu, Chu-Yi
, p. 3208 - 3221 (2013/06/27)
A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are precursors of various azepane iminosugars.