1427031-99-9Relevant academic research and scientific papers
Total synthesis of 13-demethyllyngbyaloside B
Fuwa, Haruhiko,Yamagata, Naoya,Saito, Asami,Sasaki, Makoto
supporting information, p. 1630 - 1633 (2013/06/27)
Total synthesis of 13-demethyllyngbyaloside B, an unnatural analogue of a marine macrolide glycoside lyngbyaloside B, has been achieved. The 14-membered macrocyclic backbone was constructed in a convergent manner via esterification and ring-closing metathesis. The bromodiene side chain was introduced by means of a Stille-type reaction and a subsequent bromodesilylation. Finally, the rhamnopyranose unit was stereoselectively introduced by glycosylation under Schmidt conditions.
