1427042-96-3Relevant academic research and scientific papers
Synthesis of a dual-purpose 2-deoxy-2-fluoro-glucopyranosyl building block
Viuff, Agnete H.,Hansen, Jacob C.,Christiansen, Anja B.,Jensen, Henrik H.
, p. 1557 - 1562 (2013)
We demonstrate a straightforward route to 1,3,6-tri-O-acetyl-4-O-benzyl-2- deoxy-2-fluoro-D-glucopyranose through potassium hydrogen fluoride opening of a Cerny epoxide under microwave irradiation followed by acetolysis. The fluoroglucose building block was used as a key intermediate in the synthesis of 2,20-dideoxy-2,20-difluoromaltose. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications1 to view the free supplemental file. Copyright Taylor & Francis Group, LLC.
