1427054-10-1

Basic information

• Product Name: 1,5-Bis(2-broMo-5-hydroxyphenyl)pentan-3-one
• Synonyms: 1,5-Bis(2-broMo-5-hydroxyphenyl)pentan-3-one;1,5-Bis(2-bromo-5-hydroxyphenyl)-3-pentanone
• CAS NO: 1427054-10-1
• Molecular Formula: C17H16Br2O3
• Molecular Weight: 428.11514
• Mol File: 1427054-10-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,5-Bis(2-broMo-5-hydroxyphenyl)pentan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Bis(2-broMo-5-hydroxyphenyl)pentan-3-one(1427054-10-1)
• EPA Substance Registry System: 1,5-Bis(2-broMo-5-hydroxyphenyl)pentan-3-one(1427054-10-1)

Safety Data

• Hazardous Substances Data: 1427054-10-1(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

It is derived from pentan-3-one by attaching two bromine atoms and two hydroxyphenyl groups to the central carbon atom.

Explanation

The compound contains two bromine atoms, which are attached to the hydroxyphenyl groups.

Explanation

It is commonly used in organic synthesis due to its ability to form complex structures through reactions with other reagents.

Explanation

The compound may be used in the production of pharmaceuticals due to its unique structure and properties.

Explanation

It is known for its use as a reagent in laboratory experiments, particularly in the field of organic chemistry.

Explanation

Due to its specific structure and properties, 1,5-bis(2-bromo-5-hydroxyphenyl)pentan-3-one is of significant interest to researchers and chemists for various applications in organic chemistry.

Derivative of pentan-3-one

Yes

Bromine atoms

Two

Hydroxyphenyl groups

Two

Application in organic synthesis

Yes

Utilization in pharmaceuticals

Potential

Use as a laboratory reagent

Yes

Interest to researchers and chemists

High

Upstream product

• 100-83-4 meta-hydroxybenzaldehyde 
• 1427054-08-7 1,5-bis(3-hydroxyphenyl)pentan-3-one 
• 881915-97-5 (1E,4E)-1,5-bis(3-hydroxyphenyl)penta-1,4-dien-3-one 

Relevant articles and documents

Catalytic asymmetric synthetic method for chiral spirodiol derivative

The invention belongs to the field of organic synthesis, and discloses a catalytic asymmetric synthetic method for a chiral spirodiol derivative. The catalytic asymmetric synthetic method comprises the following step: with chiral phosphoric acid as a catalyst, subjecting a compound as shown in a formula I in the specification and/or a compound as shown in a formula II in the specification to a reaction so as to obtain a product. In the formula I and the formula II, R1, R2, R4, R5, R6 and R7 are independently selected from any groups; and R3 is an alkyl group. The catalytic asymmetric synthetic method is a convenient, rapid and direct method for construction of a chiral spirodiol structure. The synthetic method provided by the invention has the advantages of high yield, good enantioselectivity, capability of tolerating a variety of functional groups, etc., can reduce the usage amount of the catalyst to 0.1 mol% during large-scale synthesis, and has application values in industrial production.

Phosphoric Acid-Catalyzed Asymmetric Synthesis of SPINOL Derivatives

Axially chiral 1,1′-spirobiindane-7,7′-diol (SPINOL) is the most fundamental and important privileged structure from which other chiral ligands containing a 1,1′-spirobiindane backbone are synthesized. Driven by the development of enantioselective syntheses of axially chiral SPINOL derivatives, we have successfully developed the first phosphoric acid-catalyzed asymmetric approach. This approach is highly convergent and functional group tolerant, efficiently providing SPINOLs in good yield with excellent enantioselectivity, thus delivering a practical and straightforward access to this privileged structure. It should be emphasized that the catalyst loading could be decreased to only 0.1 mol% for the preparative-scale synthesis. Furthermore, 4,4′-dimethyl-SPINOL-phosphoric acid was synthesized and applied to catalyze the model reaction for synthesis of enantioenriched SPINOL derivatives.