1427158-29-9

Basic information

• Product Name: 2-chloro-N-(3-chlorobenzo[d]isothiazol-7-yl)-5-(pivalamidomethyl)benzamide
• Synonyms: 2-chloro-N-(3-chlorobenzo[d]isothiazol-7-yl)-5-(pivalamidomethyl)benzamide
• CAS NO: 1427158-29-9
• Molecular Weight: 436.362
• Mol File: 1427158-29-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-N-(3-chlorobenzo[d]isothiazol-7-yl)-5-(pivalamidomethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-(3-chlorobenzo[d]isothiazol-7-yl)-5-(pivalamidomethyl)benzamide(1427158-29-9)
• EPA Substance Registry System: 2-chloro-N-(3-chlorobenzo[d]isothiazol-7-yl)-5-(pivalamidomethyl)benzamide(1427158-29-9)

Safety Data

• Hazardous Substances Data: 1427158-29-9(Hazardous Substances Data)

Upstream product

• 7716-66-7 3-chloro-1,2-benzisothiazole 
• 41533-75-9 3-chloro-7-nitro-1,2-benzisothiazole 
• 1381846-41-8 methyl 2-chloro-5-(pivalamidomethyl)benzoate 
• 148193-31-1 3-chlorobenzo[d]isothiazol-7-amine 

Downstream Products

• 1427158-67-5 2-chloro-5-(pivalamidomethyl)-N-(3-((4-(trifluoromethyl)phenyl)amino)benzo[d]isothiazol-7-yl)benzamide 

Relevant articles and documents

SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS mPGES-1 INHIBITORS

The present invention relates to bicyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (m PGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthama, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases. (I)