1427180-43-5

Basic information

• Product Name: 3,5-dimethoxy-N-(pivaloyloxy)benzamide
• Synonyms: 3,5-dimethoxy-N-(pivaloyloxy)benzamide
• CAS NO: 1427180-43-5
• Molecular Weight: 281.309
• Mol File: 1427180-43-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,5-dimethoxy-N-(pivaloyloxy)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-dimethoxy-N-(pivaloyloxy)benzamide(1427180-43-5)
• EPA Substance Registry System: 3,5-dimethoxy-N-(pivaloyloxy)benzamide(1427180-43-5)

Safety Data

• Hazardous Substances Data: 1427180-43-5(Hazardous Substances Data)

Upstream product

• 710311-79-8 N-hydroxy-3,5-dimethoxybenzamide 
• 1293990-73-4 O-pivaloylhydroxylamine trifluoromethanesulfonate salt 
• 17213-57-9 3,5-dimethoxybenzoyl chloride 
• 1538-75-6 2,2-dimethylpropanoic anhydride 

Relevant articles and documents

Formal Lossen Rearrangement/[3+2] Annulation Cascade Catalyzed by a Modified Cyclopentadienyl RhIII Complex

It has been established that a cyclopentadienyl RhIII complex with two phenyl groups and a pendant amide moiety catalyzes the formal Lossen rearrangement/[3+2] annulation cascade of N-pivaloyl benzamides and acrylamides with alkynes leading to substituted indoles and pyrroles. Mechanistic studies revealed that this cascade reaction proceeds via not the Lossen rearrangement to form anilides or enamides but C?H bond cleavage, alkyne insertion, and the formal Lossen rearrangement.