142719-82-2

Basic information

• Product Name: 3H-Diazirine, 3-(3-bromophenyl)-3-(trifluoromethyl)-
• CAS NO: 142719-82-2
• Molecular Formula: C8H4BrF3N2
• Molecular Weight: 265.032
• Mol File: 142719-82-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3H-Diazirine, 3-(3-bromophenyl)-3-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Diazirine, 3-(3-bromophenyl)-3-(trifluoromethyl)-(142719-82-2)
• EPA Substance Registry System: 3H-Diazirine, 3-(3-bromophenyl)-3-(trifluoromethyl)-(142719-82-2)

Safety Data

• Hazardous Substances Data: 142719-82-2(Hazardous Substances Data)

Upstream product

• 142719-80-0 1-(3-bromophenyl)-2,2,2-trifluoro-1-ethanone O-(p-tolylsulfonyl)oxime 
• 139486-41-2 1-(3-bromophenyl)-2,2,2-trifluoro-1-ethanone oxime 
• 655-26-5 m-bromotrifluoroacetone 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 142719-81-1 3-(3-bromophenyl)-3-(trifluoromethyl)diaziridine 

Downstream Products

• 142992-88-9 2,3-dihydroxy-3-(3-<3-(trifluoromethyl)diazirin-3-yl>phenyl)propionic acid 
• 142743-47-3 3-<3-(trifluoromethyl)diazirin-3-yl>cinnamic acid 

Relevant articles and documents

Photochemical Cyclopropenation of Alkynes with Diazirines as Carbene Precursors in Continuous Flow

An efficient synthesis of 3-trifluoromethyl-3-aryl-cyclopropenes via the cyclopropenation reaction of alkynes with photolytically generated carbenes from diazirine compounds is described. This reaction is performed in continuous flow using readily available LEDs under mild reaction conditions. This new and efficient method describes the synthesis of 25 examples of 3-trifluoromethyl-3-aryl-cyclopropenes with yields up to 97%, achieved in continuous flow with a 5 min residence time. Control experiments highlighted that diazirines are more efficient than diazo compounds for this transformation.