1427203-23-3

Basic information

• Product Name: N-benzyloxy-3-cyanopropanamide
• Synonyms: N-benzyloxy-3-cyanopropanamide
• CAS NO: 1427203-23-3
• Molecular Weight: 204.228
• Mol File: 1427203-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyloxy-3-cyanopropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyloxy-3-cyanopropanamide(1427203-23-3)
• EPA Substance Registry System: N-benzyloxy-3-cyanopropanamide(1427203-23-3)

Safety Data

• Hazardous Substances Data: 1427203-23-3(Hazardous Substances Data)

Upstream product

• 16051-87-9 3-cyanopropanoic acid 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 

Downstream Products

• 1427203-26-6 N-(benzyloxy)-3-cyano-N-methylpropanamide 
• 1427203-29-9 N-(benzyloxy)-N-methyl-3-(1H-tetrazol-5-yl)propanamide? 

Relevant articles and documents

Synthesis of tetrazole analogues of phosphonohydroxamic acids: An attempt to improve the inhibitory activity against the DXR

This work is focused on the design of new antimicrobial drugs and on the development of lipophilic inhibitors of the DXR, the second enzyme of the MEP pathway for the biosynthesis of isoprene units in most bacteria, by replacing the phosphonate group of fosmidomycin derivatives by a tetrazoyl moiety capable of multiple hydrogen bonding. The N- and C-substituted tetrazole analogues of phosphonohydroxamate inhibitors were synthesized and tested on the DXR of Escherichia coli. This work points out the hypothesis that the phosphonate/phosphate recognition site might be too rigid to accommodate other functional groups.