1427282-75-4Relevant academic research and scientific papers
Highly diastereoselective synthesis of 3-indolylglycines via an asymmetric oxidative heterocoupling reaction of a chiral nickel(ii) complex and indoles
Lin, Daizong,Wang, Jiang,Zhang, Xu,Zhou, Shengbin,Lian, Jie,Jiang, Hualiang,Liu, Hong
, p. 2575 - 2577 (2013)
The asymmetric synthesis of 3-indolylglycine derivatives was achieved by an oxidative heterocoupling reaction. This method for the selective C-3 functionalization of unprotected indoles with the chiral equivalent of a nucleophilic glycine nickel(ii) complex afforded adducts with high diastereoselectivities. The decomposition of adducts readily afforded 3-indolylglycine derivatives in high yields.
