142729-91-7Relevant academic research and scientific papers
Stereoselective synthesis of α-methyl and α-alkyl ketones from esters and alkenes: Via cyclopropanol intermediates
Barysevich, Maryia V.,Kazlova, Volha V.,Kukel, Aliaksandr G.,Liubina, Aliaksandra I.,Hurski, Alaksiej L.,Zhabinskii, Vladimir N.,Khripach, Vladimir A.
, p. 2800 - 2803 (2018/03/21)
Alkenes bearing a stereocenter in the allylic position were found to undergo Kulinkovich hydroxycyclopropanation with good diastereoselectivity. For the isomerization of the resulting cyclopropanols to diastereomerically enriched α-methyl ketones, a new mild regioselective method has been developed. A sequence of stereoselective cyclopropanation and cyclopropanol ring opening was successfully employed for the construction of the C20 stereocenter in steroids.
The prins reaction using ketones: Rationalization and application toward the synthesis of the portentol skeleton
Jacolot, Maiwenn,Jean, Mickael,Levoin, Nicolas,Van De Weghe, Pierre
, p. 58 - 61 (2012/02/14)
We report a TMSI-promoted Prins cyclization reaction with ketones as carbonyl partners to prepare polysubstituted chiral spirotetrahydropyrans. In the presence of racemic 2-methylcyclohexanone a dynamic kinetic resolution occurred affording one stereoisom
A Simple Preparative Method for Isopropenyl and Vinyl Groups from Ketones
Mandai, Tadakatsu,Suzuki, Sadahiro,Murakami, Taro,Fujita, Mitsugu,Kawada, Mikio,Tsuji, Jiro
, p. 2987 - 2990 (2007/10/02)
The palladium-catalyzed regioselective hydrogenolysis is applied to a simple preparation of isopropenyl and vinyl groups from ketones. Key words.Palladium-catalyzed hydrogenolysis with formic acid, Allyl formates, Allyl carbonates
