1427305-71-2Relevant academic research and scientific papers
One-step formation of N-alkenyl-malonamides and N-alkenyl-thiomalonamides from carbamoyl meldrum's acids
Punda, Pawel,Makowiec, Slawomir
, p. 1362 - 1367 (2013/05/09)
A one-pot synthesis for the preparation of N-alkenyl-malonamides and N-alkenyl-thiomalonamides was developed. 5-[Hydroxy/mercapto(aryl/alkylamino) methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione act as a source of ketenes that react with the tautomeric form of alkyl-(2-phenyl-propylidene)-amines. A possible [2 + 2] or [4 + 2] cycloaddition product of ketene to imines was not observed.
