1427310-11-9

Basic information

• Product Name: 2-(4-hydroxy-1,2,5-oxadiazol-3-yl)-1-(p-tolyl)ethanone
• Synonyms: 2-(4-hydroxy-1,2,5-oxadiazol-3-yl)-1-(p-tolyl)ethanone
• CAS NO: 1427310-11-9
• Molecular Weight: 218.212
• Mol File: 1427310-11-9.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-hydroxy-1,2,5-oxadiazol-3-yl)-1-(p-tolyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-hydroxy-1,2,5-oxadiazol-3-yl)-1-(p-tolyl)ethanone(1427310-11-9)
• EPA Substance Registry System: 2-(4-hydroxy-1,2,5-oxadiazol-3-yl)-1-(p-tolyl)ethanone(1427310-11-9)

Safety Data

• Hazardous Substances Data: 1427310-11-9(Hazardous Substances Data)

Upstream product

• 1427310-05-1 5-(p-tolyl)isoxazole-3-hydroxamic acid 
• 517870-14-3 methyl 5-(p-tolyl)isoxazole-3-carboxylate 
• 88958-29-6 5-(4-methylphenyl)-1,2-oxazole-3-carbonyl chloride 
• 33282-21-2 5-(4-methylphenyl)isoxazole-3-carboxylic acid 

Relevant articles and documents

Mononuclear heterocyclic rearrangement of 5-arylisoxazole-3-hydroxamic acids into 3,4-substituted 1,2,5-oxadiazoles

By a series of successive transformations, 5-arylisoxazole-3-carboxylic acids (aryl=phenyl, p-tolyl, 2,5-dimethylphenyl) have been converted into 5-arylisoxazole-3-hydroxamic acids, which undergo rearrangement by the action of aqueous KOH to form 3,4-substituted 1,2,5-oxadiazoles. The structure of one of them, 1-(2,5-dimethylphenyl)-2-(4-hydroxy-1,2,5-oxadiazol-3-yl)ethanone, has been confirmed by single crystal X-ray analysis. Georg Thieme Verlag Stuttgart New York.