1427330-75-3

Basic information

• Product Name: 3-(benzo[d]imidazol-2-yl)-2-(2-methoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one
• Synonyms: 3-(benzo[d]imidazol-2-yl)-2-(2-methoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one
• CAS NO: 1427330-75-3
• Molecular Weight: 370.411
• Mol File: 1427330-75-3.mol

Chemical Properties

• CAS DataBase Reference: 3-(benzo[d]imidazol-2-yl)-2-(2-methoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(benzo[d]imidazol-2-yl)-2-(2-methoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one(1427330-75-3)
• EPA Substance Registry System: 3-(benzo[d]imidazol-2-yl)-2-(2-methoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one(1427330-75-3)

Safety Data

• Hazardous Substances Data: 1427330-75-3(Hazardous Substances Data)

Upstream product

• 934-32-7 1H-benzimidazol-2-amine 
• 118-48-9 isatoic anhydride 
• 135-02-4 ortho-anisaldehyde 

Relevant articles and documents

Preparation, characterization and catalytic application of nano-Fe3O4-DOPA-SnO2 having high TON and TOF for non-toxic and sustainable synthesis of dihydroquinazolinone derivatives

A novel class of heterogeneous magnetically separable nano catalysts was designed by encapsulating SnO2 on nano-Fe3O4-DOPA. After the successful characterization of the synthesized catalyst by FT-IR, SEM, TEM, EDX, TGA, po

One-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones by Fe3O4@SiO2-imid-PMAn nano-catalyst under ultrasonic irradiation and reflux conditions

Abstract: Fe3O4@SiO2-imid-PMAn efficiently catalyzes the condensation reaction of isatoic anhydride, aldehydes, and primary amines or ammonium salts to afford the corresponding 2,3-dihydroquinazolin-4(1H)-one derivatives under ultrasonic irradiation or reflux conditions. This method gives notable advantages such as operational simplicity, excellent yields, short reaction times, and absence of any tedious workup or purification. In addition, the excellent catalytic performance and the easy preparation, thermal stability, and separation of the catalyst make it a good heterogeneous system and a useful alternative to other heterogeneous catalysts. Also, the aforementioned nanocatalyst can be easily recovered by a magnetic field and reused for subsequent reactions for at least six times without noticeable deterioration in catalytic activity and reaction yield. Graphical abstract: [Figure not available: see fulltext.]

New applications of phosphoric acid supported on alumina (H 3PO4-Al2O3) as a reusable heterogeneous catalyst for preparation of 2,3-dihydroquinazoline-4(1H)-ones, 2H-indazolo[2,1-b]phthalazinetriones, and benzo[4,5]imidazo[1,2-a]pyrimidines

An eco-friendly procedure for synthesis of 2,3-dihydroquinazoline-4(1H)- one, 2H-indazolo[2,1-b]phthalazinetrione, and benzo[4,5]imidazo[1,2-a]pyrimidine derivatives by three-component reaction, with phosphoric acid supported on alumina as catalyst, is described. Noticeable features of the method are that it is solvent-free, work-up is easy, yields are excellent, and the catalyst is reusable.