1427356-24-8 Usage
General Description
3-Azabicyclo[3.2.1]octan-8-one hydrochloride, also known as Pentylenetetrazol, is a chemical compound that is used in scientific research to induce seizures in experimental animals for the purpose of studying epilepsy and anticonvulsant drugs. It is a central nervous system stimulant and has been used to induce convulsions in animals for over a century. Pentylenetetrazol is also used in the development of new drugs for treating epilepsy and other neurological disorders. Additionally, it has been studied for its potential in treating depression and anxiety disorders. The hydrochloride form of this compound is commonly used in research settings due to its stability and solubility in water.
Check Digit Verification of cas no
The CAS Registry Mumber 1427356-24-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,7,3,5 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1427356-24:
(9*1)+(8*4)+(7*2)+(6*7)+(5*3)+(4*5)+(3*6)+(2*2)+(1*4)=158
158 % 10 = 8
So 1427356-24-8 is a valid CAS Registry Number.
1427356-24-8Relevant articles and documents
RET inhibitor, pharmaceutical composition and application thereof
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Paragraph 0439; 0440, (2021/03/31)
The invention belongs to the field of medicines, and relates to an RET inhibitor, a pharmaceutical composition and application thereof, specifically to a compound as shown in a formula (I), or a stereoisomer, a geometrical isomer, a tautomer, nitrogen oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug of the compound as shown in the formula (I). The invention also relates to a pharmaceutical composition comprising the compound, and use of the compound and the pharmaceutical composition thereof in manufacture of medicine, wherein the medicine is particularly used for treatment and prevention of diseases and disorders associated with available RET, including cancers, irritable bowel syndrome and/or pain associated with irritable bowel syndrome.
