1427476-05-8

Basic information

• Product Name: 4-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)pyridine
• CAS NO: 1427476-05-8
• Molecular Weight: 223.277
• Mol File: 1427476-05-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)pyridine(1427476-05-8)
• EPA Substance Registry System: 4-(1-phenyl-4,5-dihydro-1H-imidazol-2-yl)pyridine(1427476-05-8)

Safety Data

• Hazardous Substances Data: 1427476-05-8(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 21381-61-3 4-(2-imidazolin-2-yl)pyridine 

Relevant articles and documents

Copper-catalyzed N -arylation of 2-imidazolines with aryl iodides

The first copper-catalyzed N-arylation of 2-imidazolines is described. The reaction affords compounds with desirable lead-like characteristics in high yield with practical simplicity under inexpensive, ligand-free conditions. The cross coupling was successful with electron-rich and electron-poor aromatic iodides. Substrates bearing halides, esters, nitriles, and free hydroxyls are well tolerated, providing reactive handles for further functionalization, as are pyridines. In addition, the regioselective N-arylation of a 4-substituted imidazoline is reported.