1427538-34-8Relevant articles and documents
Rational design of apoptosis signal-regulating kinase 1 inhibitors: Discovering novel structural scaffold
Volynets, Galyna P.,Bdzhola, Volodymyr G.,Golub, Andriy G.,Synyugin, Anatoliy R.,Chekanov, Maksym A.,Kukharenko, Oleksandr P.,Yarmoluk, Sergiy M.
, p. 104 - 115 (2013/04/23)
Increased activity of apoptosis signal-regulating kinase 1 (ASK1) is associated with a number of human disorders and the inhibitors of ASK1 may become important compounds for pharmaceutical application. Here we report novel ASK1 inhibitor scaffold, namely