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1427548-48-8

C33H32ClN5O2S2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1427548-48-8 Structure

  • Basic information

    1. Product Name: C33H32ClN5O2S2
    2. Synonyms: C33H32ClN5O2S2
    3. CAS NO:1427548-48-8
    4. Molecular Formula:
    5. Molecular Weight: 630.234
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1427548-48-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C33H32ClN5O2S2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C33H32ClN5O2S2(1427548-48-8)
    11. EPA Substance Registry System: C33H32ClN5O2S2(1427548-48-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1427548-48-8(Hazardous Substances Data)

1427548-48-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1427548-48-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,7,5,4 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1427548-48:
(9*1)+(8*4)+(7*2)+(6*7)+(5*5)+(4*4)+(3*8)+(2*4)+(1*8)=178
178 % 10 = 8
So 1427548-48-8 is a valid CAS Registry Number.

1427548-48-8Downstream Products

1427548-48-8Relevant articles and documents

Novel N-indolylmethyl substituted olanzapine derivatives: Their design, synthesis and evaluation as PDE4B inhibitors

Gorja, Dhilli Rao,Mukherjee, Soumita,Meda, Chandana Lakshmi T.,Deora, Girdhar Singh,Lalith Kumar,Jain, Ankit,Chaudhari, Girish H.,Chennubhotla, Keerthana S.,Banote, Rakesh K.,Kulkarni, Pushkar,Parsa, Kishore V. L.,Mukkanti,Pal, Manojit

, p. 2075 - 2079 (2013)

A new strategy for converting antipsychotic drug olanzapine into PDE4 inhibitors is described via the design and Pd/C mediated synthesis of novel N-indolylmethyl olanzapine derivatives. One compound showed good inhibition (IC50 1.1 μM) and >10 fold selectivity towards PDE4B over D that was supported by docking studies. This compound also showed significant inhibition of TNF-α and no major toxicities in cell lines and a zebrafish embryo model except the teratogenic effects to be re-assessed in rodents. The Royal Society of Chemistry 2013.

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