142777-75-1

Upstream product

• 31848-92-7 1-chloro-5-ethylheptan-5-ol 
• 108-98-5 thiophenol 
• 1575-61-7 5-Chlorovaleroyl chloride 
• 14633-31-9 1-chloro-4-(phenylthio)butane 
• 96-22-0 pentan-3-one 

Downstream Products

• 142777-79-5 (S)-4-Benzenesulfonyl-2-{(1R,3aS,7aR)-4-[2-[(3R,5R)-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexylidene]-eth-(E)-ylidene]-7a-methyl-octahydro-inden-1-yl}-8-ethyl-8-triethylsilanyloxy-decan-3-ol 
• 142777-80-8 (1R,3aS,7aR)-4-[2-[(3R,5R)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexylidene]-eth-(E)-ylidene]-1-((E)-(R)-7-ethyl-1-methyl-7-triethylsilanyloxy-non-2-enyl)-7a-methyl-octahydro-indene 
• 142777-81-9 Δ²²,22E,19-nor-24,24-dihomo-26,27-dihomo-1α,25-dihydroxyvitamin D3 
• 125448-35-3 (5-Benzenesulfonyl-1,1-diethyl-pentyloxy)-triethyl-silane 
• 142777-76-2 7-Benzenesulfonyl-3-ethyl-heptan-3-ol 

Relevant academic research and scientific papers

The superiority of properly prepared lithium 1-N,N-dimethylaminonaphthalenide (LDMAN) over other aromatic radical-anions for the generation of organolithiums by reductive lithiation

The use of lithium 1-N,N-dimethylaminonaphthalenide (LDMAN) is found to be considerably superior in yield, ease of operation, and cost to the far more widely used lithium p,p′-di-tert-butylbiphenylide (LDBB) in reductive lithiations by aromatic radical-an

1α-Hydroxy-19-nor-vitamin D C-22 aldehyde. A valuable intermediate in the synthesis of side chain modifed 1α,25-dihydroxy-19-nor-vitamin D3

A side chain homologated 1α,25-dihydroxy-19-nor-vitamin D3 analog was prepared in a double convergent synthesis with 1α-hydroxy-19-nor-vitamin D C-22 aldehyde as a key intermediate.