142822-34-2

Upstream product

• 142822-32-0 4-{(S)-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-methyl}-1-trityl-1H-imidazole 
• 142822-29-5 (S)-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-(1-trityl-1H-imidazol-4-yl)-methanol 
• 67373-56-2 chlorodimethyl(1,1,2-trimethylpropyl)silane 
• 142822-33-1 (2R,3S)-3-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-3-(1-trityl-1H-imidazol-4-yl)-propane-1,2-diol 

Downstream Products

• 142822-35-3 4-{(S)-2-Chloro-1-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-allyl}-1-trityl-1H-imidazole 
• 142822-36-4 4-{(1S,2S)-3-Azido-2-chloro-1-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-propyl}-1-trityl-1H-imidazole 
• 142822-38-6 4-(4-{(1S,2S)-3-Azido-2-chloro-1-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-propyl}-1H-imidazol-2-ylazo)-benzoic acid methyl ester 

Relevant academic research and scientific papers

Synthese Stereoselective de la Girolline

Desaminogirollines syn 2'S,3'S and 2'R,3'R have been prepared from N1-camphosulfonamide 4-carboxaldehyde imidazole and their diastereomeric derivatives have been separated.The stereoselective synthesis of chiral natural girolline has been achieved from D(-)arabinose : this ose is condensed with formamidine acetate to obtain a 4(5)--imidazole; the side-chain is chlorinated before being aminated via an azido compound and the 2-amino group of girolline is obtained by rhodium catalytic reduction of the 2-diazo derivative.Key Words: girolline synthesis; 2-aminoimidazole; D(-)-arabinose; 4(5)imidazole; rhodium reduction.