142823-95-8Relevant articles and documents
A SYNTHETIC METHOD FOR UNSYMMETRICAL DISULFIDES OF CYSTEINE: THE BIS-CYSTEINE DISULFIDE OF meso-2,3-DIMERCAPTOSUCCINIC ACID.
Polt, Robin,Li, Yushun,Fernando, Quintus,Rivera, Mario
, p. 2961 - 2964 (2007/10/02)
meso-Dimercaptosuccinic acid (DMSA) is the drug of choice for the treatment of lead-poisoning.DMSA is excreted in the urine of lead-poisoned rabbits as a conjugate with two molecules of cysteine.To confirm this, and to examine the hypothesis that DMSA may be acting as a pro-drug, we have synthesized the DMSA-bis-disulfide using a novel methodology based on the use of sulfenimides derived from cysteine.