1428261-72-6Relevant academic research and scientific papers
Discovery and SAR study of 2-(1-propylpiperidin-4-yl)-3H-imidazo[4,5-c]pyridine-7-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) for the treatment of cancer
Zhu, Qihua,Wang, Xueyan,Hu, Yan,He, Xiaorong,Gong, Guoqing,Xu, Yungen
, p. 6551 - 6559 (2015)
A series of imidazo[4,5-c]pyridine-7-carboxamide derivatives as poly(ADP-ribose) polymerase (PARP) inhibitors have been developed. All target compounds were evaluated for their PARP-1 inhibitory activity and some were further assessed for cellular potency
Design, synthesis and biological evaluation of novel imidazo[4,5-c] pyridinecarboxamide derivatives as PARP-1 inhibitors
Zhu, Qihua,Wang, Xuyan,Chu, Zhaoxing,He, Guangwei,Dong, Guangping,Xu, Yungen
, p. 1993 - 1996 (2013/04/24)
A series of novel cyclic amine-substituted imidazo[4,5-c] pyridinecarboxamide analogs were designed and synthesized. All the target compounds were evaluated for their PARP inhibition activity, and the result indicated that most of the compounds possessed
