142827-05-2Relevant articles and documents
New methods for the synthesis of 3'-S-phosphorothiolate internucleoside linkages
Vyle,Li,Cosstick
, p. 3017 - 3020 (2007/10/02)
Efficient procedures are described for the synthesis of dinucleoside phosphorothiolates using either a Michaelis-Arbusov-type reaction or a phosphotriester approach.
SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING 3'-THIOTHYMIDINE
Cosstick, Richard,Vyle, Joseph S.
, p. 4693 - 4696 (2007/10/02)
A 5'-O-monomethoxytritylthymidine-3'-S-thiophosphoramidite (3) has been used to prepare oligodeoxynucleotides containing 3'-thiothymidine on a solid phase support.The intermediate thiophosphites are most efficiently oxidised using tetrabutylammonium periodate.