1428338-33-3Relevant academic research and scientific papers
Pd-catalyzed multidehydrogenative cross-coupling between (Hetero)arenes and nitroethane to construct β-aryl nitroethylenes
Zhang, Min,Hu, Peng,Zhou, Jun,Wu, Ge,Huang, Shijun,Su, Weiping
supporting information, p. 1718 - 1721 (2013/06/26)
The Pd-catalyzed multidehydrogenative cross-coupling reactions of arenes with nitroethane are described. The established methods afford β-aryl nitroethylenes that are an important class of synthetic intermediates and biologically active compounds in an atom- and step-economical fashion. The reactions were applicable to substituted benzenes and a variety of heterocycles such as benzothiophenes, benzofurans, and indoles. Mechanistic experiments indicated that β-nitroethylbenzene might be the intermediate in this transformation.
