1428341-13-2

Basic information

• Product Name: tert-butyl trans-4-amino-3-methylpiperidine-1-carboxylate
• Synonyms: tert-butyl trans-4-amino-3-methylpiperidine-1-carboxylate;trans-tert-butyl 4-amino-3-methylpiperidine-1-carboxylate
• CAS NO: 1428341-13-2
• Molecular Formula: C11H22N2O2
• Molecular Weight: 214.30458
• Mol File: 1428341-13-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 287.8±33.0 °C(Predicted)
• Appearance: /
• Density: 1.009±0.06 g/cm3(Predicted)
• PKA: 10.12±0.40(Predicted)
• CAS DataBase Reference: tert-butyl trans-4-amino-3-methylpiperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl trans-4-amino-3-methylpiperidine-1-carboxylate(1428341-13-2)
• EPA Substance Registry System: tert-butyl trans-4-amino-3-methylpiperidine-1-carboxylate(1428341-13-2)

Safety Data

• Hazardous Substances Data: 1428341-13-2(Hazardous Substances Data)

Usage

Uses

tert-?Butyl trans-?4-?amino-?3-?methylpiperidine-?1-?carboxylate is a reagent used in the preparation of chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives.

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 181269-69-2 tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate 
• 723308-57-4 (3S,4S)-3-methyl-4-(1-(R)-phenyl-ethylamino)-piperidine-1-carboxylic acid tert-butyl ester 
• 723308-56-3 (3R,4R)-3-methyl-4-(1-(S)-phenyl-ethylamino)-piperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 396133-35-0 3-methylpiperidin-4-amine 
• 1186230-35-2 (rac)-(cis/trans)-N-(3-methyl-piperidin-4-yl)-2-phenyl-acetamide 

Relevant articles and documents

PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

4,6-DIAMINONICOTINAMIDE COMPOUND

[Problem] The present invention provides a 4,6-diaminonicotinamide compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for treating diseases caused by undesirable and/or abnormal cytokine signal transduction. [Means for Solution] The present inventors have extensively studied compounds having a JAK3 inhibitory action, and as a result, they have found that a 4,6-diaminonicotinamide compound which is the compound of the present invention has an excellent JAK3 inhibitory action and is useful as an agent for preventing or treating diseases caused by undesirable and/or abnormal cytokine signal transduction, thereby completing the present invention.

COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE

Compounds of formula (I) or a salt thereof are provided: (I) wherein R4, R5, R6, Q and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic