142835-99-2Relevant academic research and scientific papers
10-Substituted 11-oxygenated (R)-aporphines: Synthesis, pharmacology, and modeling of 5-HT(1A) receptor interactions
Hedberg, Martin H.,Jansen, Johanna M.,Nordvall, Gunnar,Hjorth, Stephan,Unelius, Lena,Johansson, Anette M.
, p. 3491 - 3502 (2007/10/03)
Derivatives of the selective serotonin 5-HT(1A) receptor agonist (R)- 11-hydroxy-10-methylaporphine (2) having various substituents in the C10- position or at the nitrogen have been synthesized from natural morphine or 6- O-acetylcodeine, respectively. Th
Facile Syntheses of Aporphine Derivatives
Hedberg, Martin H.,Johansson, Anette M.,Hacksell, Uli
, p. 845 - 846 (2007/10/02)
New and efficient synthetic routes, utilizing palladium-catalysed reactions, provide (R)-11-hydroxy-10-methylaporphine 2 and (R)-11-hydroxyaporphine 3 from natural morphine 4.
