1428532-49-3

Basic information

• Product Name: (S)-1-(4-(4-chloro-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea
• Synonyms: (S)-1-(4-(4-chloro-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea
• CAS NO: 1428532-49-3
• Molecular Weight: 362.819
• Mol File: 1428532-49-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-1-(4-(4-chloro-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(4-(4-chloro-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea(1428532-49-3)
• EPA Substance Registry System: (S)-1-(4-(4-chloro-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea(1428532-49-3)

Safety Data

• Hazardous Substances Data: 1428532-49-3(Hazardous Substances Data)

Upstream product

• 350595-57-2 (S)-3-methylmorpholine 
• 874290-99-0 1-methyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea 
• 1428532-47-1 (S)-4-(4,6-dichloro-1,3,5-triazin-2-yl)-3-methylmorpholine 

Downstream Products

• 1428532-50-6 (S)-1-(4-(4-(5-fluoro-2-(methylthio)phenyl)-6-(3-methylmorpholin-4-yl)-1,3,5-triazin-2-yl)phenyl)-3-methylurea 
• 1428531-94-5 (S)-1-(4-(4-(5-fluoro-2-(methylsulfonyl)phenyl)-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea 

Relevant articles and documents

MORPHOLINO SUBSTITUTED UREA OR CARBAMATE DERIVATIVES AS MTOR INHIBITORS

The invention relates to compounds of formula (I) wherein m, n, R1, T0 and T1 have the meaning as cited in the description and the claims. The compounds are useful as inhibitors of mTOR for the treatment or prophylaxis of mTOR related diseases and disorders. The invention also relates to pharmaceutical compositions including said compounds as well as methods of treating mTOR related diseases.