1428559-06-1

Basic information

• Product Name: 2’-(((5-(4”-fluorobenzoyl)-5H-[1,2,4]triazino[5,6-b]indol3-yl)thio)methyl)benzonitrile
• Synonyms: 2’-(((5-(4”-fluorobenzoyl)-5H-[1,2,4]triazino[5,6-b]indol3-yl)thio)methyl)benzonitrile
• CAS NO: 1428559-06-1
• Molecular Weight: 439.472
• Mol File: 1428559-06-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2’-(((5-(4”-fluorobenzoyl)-5H-[1,2,4]triazino[5,6-b]indol3-yl)thio)methyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2’-(((5-(4”-fluorobenzoyl)-5H-[1,2,4]triazino[5,6-b]indol3-yl)thio)methyl)benzonitrile(1428559-06-1)
• EPA Substance Registry System: 2’-(((5-(4”-fluorobenzoyl)-5H-[1,2,4]triazino[5,6-b]indol3-yl)thio)methyl)benzonitrile(1428559-06-1)

Safety Data

• Hazardous Substances Data: 1428559-06-1(Hazardous Substances Data)

Upstream product

• 292057-70-6 3-((2’-cyanobenzyl)thio)-5H-[1,2,4]triazino[5,6-b]indole 
• 151093-41-3 α-bromo-4-fluoroacetophenone 
• 28668-95-3 3-mercapto-5H-1,2,4-triazino[5,6-b]indole 
• 91-56-5 indole-2,3-dione 

Relevant articles and documents

Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists

The cannabinoid receptor 2 (CB2R) has been linked with the regulation of inflammation, and selective receptor activation has been proposed as a target for the treatment of a range of inflammatory diseases such as atherosclerosis and arthritis.

CANNABINOID-2-RECEPTOR AGONISTS

The present invention relates to cannabinnoid-2-receptor (CB2R) agonist compounds. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them and to their use as therapeutic agents for the treatment and/or prevention of diseases or conditions in which CB2R stimulation is beneficial (especially inflammatory conditions).