1428620-37-4

Basic information

• Product Name: methyl 2-{5-amino-2-[(4-methylbenzoyl)imino]benzo[d]thiazol-3(2H)-yl}butanoate
• Synonyms: methyl 2-{5-amino-2-[(4-methylbenzoyl)imino]benzo[d]thiazol-3(2H)-yl}butanoate
• CAS NO: 1428620-37-4
• Molecular Weight: 383.471
• Mol File: 1428620-37-4.mol

Chemical Properties

• CAS DataBase Reference: methyl 2-{5-amino-2-[(4-methylbenzoyl)imino]benzo[d]thiazol-3(2H)-yl}butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-{5-amino-2-[(4-methylbenzoyl)imino]benzo[d]thiazol-3(2H)-yl}butanoate(1428620-37-4)
• EPA Substance Registry System: methyl 2-{5-amino-2-[(4-methylbenzoyl)imino]benzo[d]thiazol-3(2H)-yl}butanoate(1428620-37-4)

Safety Data

• Hazardous Substances Data: 1428620-37-4(Hazardous Substances Data)

Upstream product

• 3196-15-4 Methyl 2-bromobutyrate 
• 333415-02-4 N-[(2-fluoro-5-nitrophenyl)carbamothioyl]-4-methyl-benzamide 
• 369-36-8 6-fluoro-3-nitroaniline 
• 874-60-2 4-methyl-benzoyl chloride 
• 955823-06-0 4-methyl-N-(5-nitrobenzo[d]thiazol-2-yl)benzamide 
• 1428620-36-3 methyl 2-{5-nitro-2-[(4-methylbenzoyl)imino]benzo[d]thiazol-3(2H)-yl}butanoate 

Downstream Products

• 1428620-38-5 methyl 2-{5-acetamido-2-[(4-methylbenzoyl)imino]benzo[d]thiazol-3(2H)-yl}butanoate 

Relevant articles and documents

PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OF ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

Provided is a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.

PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention provides a phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt can selectively inhibit the protein-protein interaction between KRS and a laminin receptor (LR), thereby inhibiting migration of cancer cells. Therefore, the phenylimide-containing benzothiazole derivative or its pharmaceutically acceptable salt may be usefully applied for preventing or treating the diseases associated with cancer cell metastasis.