1428641-51-3Relevant academic research and scientific papers
An efficient and diastereoselective synthesis of hydrazino amides via a novel one-pot three-component reaction
Ramezanpour, Sorour,Balalaie, Saeed,Rominger, Frank,Bijanzadeh, Hamid Reza
, p. 3480 - 3485 (2013)
An efficient one-pot three-component synthesis of a series of α-hydrazino amides, obtained in high diastereoselectivity and yield, was realized starting from cyclic ketones, hydrazides, and isocyanides in the presence of 10 mol % p-TsOH in ethanol at room temperature. The synthetic protocol was optimized and the observed diastereoselectivity was measured using 1H NMR spectroscopy.
