1428644-27-2

Upstream product

• 59-49-4 2-Benzoxazolinone 
• 1428644-19-2 3-[(4-amino-5-thioxo-1,2,4-triazol-3-yl)methyl]-2(3H)-benzoxazolone 
• 459-57-4 4-fluorobenzaldehyde 
• 13610-51-0 ethyl (2‐benzoxazolinone‐3‐yl)acetate 

Relevant academic research and scientific papers

Schiff bases of 3-[(4-amino-5-thioxo-1,2,4-triazole-3-yl) methyl]-2(3H)-benzoxazolone derivatives: Synthesis and biological activity

New Schiff base derivatives of 3-[(4-amino-5-thioxo-1,2,4-triazole-3-yl) methyl]-2(3H)-benzoxazolone with aromatic aldehydes have been synthesized under microwave irradiation. Structures of the synthesized compounds were confirmed by IR, 1H-NMR and elemental analysis. Variable, but modest antimicrobial and antitubercular activity against the investigated strains of bacteria and fungi were observed. Among the derivatives obtained, 4-bromophenylmethylidene derivative 5j revealed significant antibacterial activity against P. aeruginosa.