1428649-20-0

Basic information

• Product Name: 8,9,10,11-tetrahydro-11-(4-methylbenzylidene)-7-(4-methylphenyl)-6H,7H-chromeno[4,3-b]chromen-6-one
• CAS NO: 1428649-20-0
• Molecular Weight: 446.546
• Mol File: 1428649-20-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8,9,10,11-tetrahydro-11-(4-methylbenzylidene)-7-(4-methylphenyl)-6H,7H-chromeno[4,3-b]chromen-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8,9,10,11-tetrahydro-11-(4-methylbenzylidene)-7-(4-methylphenyl)-6H,7H-chromeno[4,3-b]chromen-6-one(1428649-20-0)
• EPA Substance Registry System: 8,9,10,11-tetrahydro-11-(4-methylbenzylidene)-7-(4-methylphenyl)-6H,7H-chromeno[4,3-b]chromen-6-one(1428649-20-0)

Safety Data

• Hazardous Substances Data: 1428649-20-0(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 104-87-0 4-methyl-benzaldehyde 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 42792-79-0 2,6-bis(4-methylbenzylidene)cyclohexanone 

Relevant articles and documents

Cyclization of α,α′-bis(substituted-benzylidene) cyclohexanones and 4-hydroxycoumarin: Synthesis of 11-benzylidene-8,9,10,11- tetrahydro-7-phenyl-6H,7H-chromeno[4,3-b]chromen-6-ones as new pyranochromene derivatives

A series of new 11-benzylidene-8,9,10,11-tetrahydro-7-phenyl-6H,7H- chromeno[4,3-b]chromen-6-ones has been synthesized through a new Michael addition domino cyclization between α,α′-bis(substituted- benzylidene)cyclohexanones and 4-hydroxycoumarin in acetic acid at reflux conditions. Very good to excellent yields of the products, operational simplicity, and simple workup are attractive features of this synthesis protocol.