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(3S,4S)-N-benzyl-3,4-pyrrolidinediyl diacetate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1428671-06-0 Structure
  • Basic information

    1. Product Name: (3S,4S)-N-benzyl-3,4-pyrrolidinediyl diacetate
    2. Synonyms: (3S,4S)-N-benzyl-3,4-pyrrolidinediyl diacetate
    3. CAS NO:1428671-06-0
    4. Molecular Formula:
    5. Molecular Weight: 277.32
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1428671-06-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (3S,4S)-N-benzyl-3,4-pyrrolidinediyl diacetate(CAS DataBase Reference)
    10. NIST Chemistry Reference: (3S,4S)-N-benzyl-3,4-pyrrolidinediyl diacetate(1428671-06-0)
    11. EPA Substance Registry System: (3S,4S)-N-benzyl-3,4-pyrrolidinediyl diacetate(1428671-06-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1428671-06-0(Hazardous Substances Data)

1428671-06-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1428671-06-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,8,6,7 and 1 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1428671-06:
(9*1)+(8*4)+(7*2)+(6*8)+(5*6)+(4*7)+(3*1)+(2*0)+(1*6)=170
170 % 10 = 0
So 1428671-06-0 is a valid CAS Registry Number.

1428671-06-0Downstream Products

1428671-06-0Relevant articles and documents

(3S,4S)-N-substituted-3,4-dihydroxypyrrolidines as ligands for the enantioselective Henry reaction

Rénio, Márcia R.R.,Sousa, Francisco J.P.M.,Tavares, Nélia C.T.,Valente, Artur J.M.,da Silva Serra, M. Elisa,Murtinho, Dina

, (2021)

The enantioselective Henry reaction is a very important and useful carbon–carbon bond forming reaction. The execution of this reaction requires the use of efficient chiral catalysts. In this work, in situ formed complexes of N-substituted dihydroxypyrrolidines, chiral ligands derived from L-tartaric acid and amines, were evaluated as catalysts in the enantioselective Henry reaction. The results showed that the nature of the N-substituent on the ligand significantly influences the outcome of the reaction. Best results were obtained using a Cu (II) complex of (3S,4S)-N-benzyl-3,4-dihydroxypyrrolidine, in the presence of DIPEA, for the reaction of aromatic aldehydes with nitromethane, at room temperature, originating products with er up to 92:8 (R:S) and conversions up to 96%. The interaction between the pyrrolidine ligand and the copper ion, in isopropanol, was followed by UV-vis spectrophotometry, showing a 1:1 stoichiometry and a binding constant of 4.4. The results obtained will contribute to the design and development of more efficient chiral catalysts for this type of reaction.

Five-membered iminocyclitol α-glucosidase inhibitors: Synthetic, biological screening and in silico studies

Guerreiro, Luis R.,Carreiro, Elisabete P.,Fernandes, Luis,Cardote, Teresa A.F.,Moreira, Rui,Caldeira, Ana T.,Guedes, Rita C.,Burke

, p. 1911 - 1917 (2013/04/23)

The design and synthesis of a small library of pyrrolidine iminocyclitol inhibitors with a structural similarity to 1,4-dideoxy-1,4-imino-d-arabitol (DAB-1) is reported. This library was specifically designed to gain a better insight into the mechanism of inhibition of glycosidases by polyhydroxylated pyrrolidines or iminocyclitols. Pyrrolidine-3,4-diol 15a and pyrrolidine-3,4-diol diacetate 15b had emerged as the most potent α-glucosidase inhibitors in the series. Docking studies performed with an homology model of α-glucosidase disclosed binding poses for compounds 15a, 15b, 16a, and 16a′ occupying the same region as the NH group of the terminal ring of acarbose and suggest a closer and stronger binding of compound 15a and 15b with the enzyme active site residues. Our studies indicate that 2 or 5-hydroxyl substituents appear to be vital for high inhibitory activity.

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