1428673-33-9

Upstream product

• 778-36-9 2,3,4,5,6-pentafluorobenzenesulfonamide 
• 832-53-1 pentafluorobenzenesulonyl chloride 
• 1428673-32-8 2,3,5,6-tetrafluoro-4-[(2-phenylethyl)thio]benzenesulfonamide 

Downstream Products

• 1604043-19-7 3-{[(1R,2S)-2-hydroxy-1,2-diphenylethyl]amino}-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-17-5 3-[((1S)-1,2,3,4-tetrahydronapthalen-1-ylamino)]-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-16-4 3-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-15-3 3-(2,3-dihydro-1H-inden-2-ylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-13-1 3-[(3,4-dimethoxybenzyl)amino]-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-12-0 3-[(2,6-dimethoxybenzyl)amino]-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-11-9 3-(cyclododecylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-10-8 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-09-5 3-morpholin-4-yl-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-18-6 3-{[(1S,2R)-2-hydroxy-1,2-diphenylethyl]amino}-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-14-2 3-(1-adamantylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]-benzenesulfonamide 
• 1604043-08-4 3-[(2-phenylethyl)amino]-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-06-2 3-(tert-butylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 
• 1604043-07-3 3-(benzylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamide 

Relevant academic research and scientific papers

FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE

Invention is related to novel compounds - fluorinated benzenesulfonamides of general formula (I). The compounds can be used in biomedicine as active ingredients in pharmaceutical formulations, because they inhibit enzymes which participate in disease progression. ˙

4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII

A series of 4-substituted-2,3,5,6-tetrafluorobenezenesulfonamides were synthesized and their binding potencies as inhibitors of recombinant human carbonic anhydrase isozymes I, II, VII, XII, and XIII were determined by the thermal shift assay, isothermal