142874-43-9Relevant articles and documents
Discovery of Benzofuran Derivatives that Collaborate with Insulin-Like Growth Factor 1 (IGF-1) to Promote Neuroprotection
Wakabayashi, Takeshi,Tokunaga, Norihito,Tokumaru, Kazuyuki,Ohra, Taiichi,Koyama, Nobuyuki,Hayashi, Satoru,Yamada, Ryuji,Shirasaki, Mikio,Inui, Yoshitaka,Tsukamoto, Tetsuya
, p. 5109 - 5114 (2016/06/13)
A series of benzofuran derivatives with neuroprotective activity in collaboration with IGF-1 was discovered using a newly developed cell-based assay involving primary neural cells prepared from rat hippocampal and cerebral cortical tissues. A structure-ac
PHENYLAZOLE COMPOUND, PRODUCTION PROCESS, AND ANTIOXIDANT DRUG
-
Page/Page column 19, (2008/06/13)
The present invention relates to a compound represented by formula (1): (wherein R represents a hydrogen atom or a C1-6 alkyl group which may be substituted, A represents an imidazolyl group or a pyrazolyl group, B represents a group represente
5-Aminocoumarans: Dual inhibitors of lipid peroxidation and dopamine release with protective effects against central nervous system trauma and ischemia
Ohkawa, Shigenori,Fukatsu, Kohji,Miki, Shokyo,Hashimoto, Tadatoshi,Sakamoto, Junko,Doi, Takayuki,Nagai, Yasuo,Aono, Tetsuya
, p. 559 - 573 (2007/10/03)
A series of 2,3-dihydro-5-benzofuranamines (5-aminocoumarans) were developed for the treatment of traumatic and ischemic central nervous system (CNS) injury. Compounds within this class were extremely effective inhibitors of lipid peroxidation in vitro an