1428871-47-9Relevant academic research and scientific papers
Selective synthesis of cyano-functionalized 2-aryl-4 h -chromenes and 2-amino-4 H -chromene-3-carbonitriles by catalyst-tuned reactions of 2-hydroxychalcones with 2-substituted acetonitriles
Yin, Guodong,Shi, Houqiang,Xu, Liqianyun,Wei, Xianhong,Tao, Qing
, p. 334 - 340 (2013/03/13)
A selective synthesis of 4H-chromenes by the reactions of 2-hydroxychalcone derivatives with acetonitriles substituted with electron-withdrawing groups is described. Under catalyst-free conditions, the reactions give cyano-functionalized 2-aryl-4H-chromenes, whereas in the presence of sodium bicarbonate, 2-amino-4H-chromene-3-carbonitriles are obtained in excellent yields. Georg Thieme Verlag Stuttgart New York.
