142893-63-8

Upstream product

• 17974-59-3 (7E)-9-ethynyl-β-ionol 
• 84188-96-5 (E)-3-(1,3-dithian-2-yl)-2-methylpropenal 

Downstream Products

• 564-87-4 (11Z)-retinal 
• 142893-61-6 all-trans-retinal propylene dithioacetal 
• 116-31-4 all-trans-Retinal 
• 472-86-6 13-cis-vitamin A aldehyde 
• 142893-62-7 8-(1,3-dithian-2-yl)-3,7-dimethyl-1-(2,6,6-trimethyl-cyclohex-1-enyl)octa-1E,4E,7E-trien-3,6-diol 

Relevant academic research and scientific papers

Low-valent titanium reductive elimination: a direct and highly stereoselective synthesis of vitamin A aldehyde and all-trans retinoic acid orthothioester

It is shown that low-valent titanium reductive elimination can be carried out in the presence of a thioacetal or an orthothioester group.The application to the synthesis of vitamin A aldehyde and all-trans retinoic acid orthothioester is described.Keywords - Ti(0) reductive elimination / vitamin A aldehyde / all-trans retinoic acid

Low-Valent Titanium Reductive Elimination: a Direct and Highly Stereoselective Synthesis of Vitamin A Aldehyde.

It was shown that the low-valent titanium reductive elimination could be carried out in presence of a thioacetal group.An application to the synthesis of vitamin A aldehyde is described.