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(R)-(+)-1,9-Fluorenylethylchloroformate, with the molecular formula C17H13ClO2, is a chemical compound that belongs to the ester class. It is synthesized from (R)-(+)-1,9-fluorenylethanol and chloroformic acid. (R)-(+)-1,9-fluorenylethylchloroformate is characterized by its ability to efficiently and selectively form chiral carbon-carbon bonds, making it a valuable asset in the field of organic synthesis.

1428936-75-7

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1428936-75-7 Usage

Uses

Used in Pharmaceutical Industry:
(R)-(+)-1,9-Fluorenylethylchloroformate is used as a key building block for the production of various pharmaceuticals. Its role in asymmetric synthesis allows for the creation of chiral compounds, which are essential in the development of many drugs due to their specific interactions with biological targets.
Used in Agrochemical Industry:
In the agrochemical sector, (R)-(+)-1,9-fluorenylethylchloroformate is utilized as a reagent in the synthesis of chiral compounds that can be used as active ingredients in pesticides and other agricultural chemicals. The chiral nature of these compounds can provide enhanced selectivity and reduced environmental impact.
Used in Fine Chemicals Production:
(R)-(+)-1,9-Fluorenylethylchloroformate is also employed in the synthesis of various fine chemicals, which are high-purity chemicals used in a wide range of applications, including fragrances, dyes, and specialty chemicals. Its ability to form chiral carbon-carbon bonds is particularly valuable in this industry, as it allows for the production of enantiomerically pure compounds with specific properties.
Used in Asymmetric Synthesis:
(R)-(+)-1,9-Fluorenylethylchloroformate is widely studied and applied in asymmetric synthesis across various industries. Asymmetric synthesis is a crucial technique in the production of enantiomerically pure compounds, which are important for their specific biological activities and reduced side effects. The use of (R)-(+)-1,9-fluorenylethylchloroformate in asymmetric synthesis contributes to the development of more effective and safer products in multiple sectors.

Check Digit Verification of cas no

The CAS Registry Mumber 1428936-75-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,8,9,3 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1428936-75:
(9*1)+(8*4)+(7*2)+(6*8)+(5*9)+(4*3)+(3*6)+(2*7)+(1*5)=197
197 % 10 = 7
So 1428936-75-7 is a valid CAS Registry Number.

1428936-75-7Relevant academic research and scientific papers

Pan-Tropic Entry Inhibitors

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Page/Page column 80; 84, (2019/10/15)

This disclsore relates to compounds according to Formula (I), salts, prodrugs and pharmaceutical formulation comprising the compound are provided herein for the treatment of CXCR4 and CCR5 related conditions. The conditions may include viral infections, a

(+)-Fluorenylethylchloroformate (FLEC)-improved synthesis for application in chiral analysis and peptidomimetic synthesis

Camerino, Michelle A.,Chalmers, David K.,Thompson, Philip E.

, p. 2571 - 2573 (2013/06/05)

An efficient synthesis of the enantiomers of fluorenylethylchloroformate (FLEC) has been achieved that allows the routine application of the reagent for the resolution of chiral amines including unusual amino acids. The utility of the fluorenylethoxycarbonyl (Feoc) group as a chiral Fmoc equivalent, for combined resolution and protection of amino acids, in solid phase peptide synthesis is also shown.

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