1428947-07-2Relevant academic research and scientific papers
Developing novel C-4 analogues of pyrrole-based antitubulin agents: Weak but critical hydrogen bonding in the colchicine site
Da, Chenxiao,Telang, Nakul,Hall, Kayleigh,Kluball, Emily,Barelli, Peter,Finzel, Kara,Jia, Xin,Gupton, John T.,Mooberry, Susan L.,Kellogg, Glen E.
, p. 417 - 421 (2013/06/26)
The synthesis, biological evaluation and molecular modeling of a series of pyrrole compounds related to 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2- carboxylic acid that evaluates and optimizes C-4 substituents are reported. The key factor for microt
