1428989-13-2Relevant academic research and scientific papers
An efficient synthesis of fluorinated azaheterocycles by aminocyclization of alkenes
Huang, Hai-Tsang,Lacy, Tyler C.,Blachut, Barbara,Ortiz, Gerardo X.,Wang, Qiu
supporting information, p. 1818 - 1821 (2013/06/04)
A general and efficient approach to important fluorinated azaheterocycles has been developed by incorporating nucleophilic fluorination into alkene difunctionalization. This intramolecular aminofluorination transformation of alkenes has been achieved via the aminocyclization of reactive unsaturated N-iodoamines, which can be generated in situ from either unsaturated N-chloramines or their amine precursors in a one-pot protocol.
