142902-34-9Relevant academic research and scientific papers
5-Aminocoumarans: Dual inhibitors of lipid peroxidation and dopamine release with protective effects against central nervous system trauma and ischemia
Ohkawa, Shigenori,Fukatsu, Kohji,Miki, Shokyo,Hashimoto, Tadatoshi,Sakamoto, Junko,Doi, Takayuki,Nagai, Yasuo,Aono, Tetsuya
, p. 559 - 573 (2007/10/03)
A series of 2,3-dihydro-5-benzofuranamines (5-aminocoumarans) were developed for the treatment of traumatic and ischemic central nervous system (CNS) injury. Compounds within this class were extremely effective inhibitors of lipid peroxidation in vitro an
Aminocoumaran derivatives, their production and use
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, (2008/06/13)
A novel aminocoumaran derivatives of the general formula (I): STR1 wherein R1 and R2 are a hydrogen atom, an acyl group, an alkoxycarbonyl group, an aliphatic group or aromatic group; R3 R4 and R5 are an optionally acylated hydroxyl optionally substituted amino group, alkoxy group or aliphatic group, or two of R3, R4 and R5 may be linked together to form a carbocyclic group; R6 and R7 are an aliphatic group and at least one of them has a methylene group at the α-position; R8 and R9 are a hydrogen atom or an aliphatic group or aromatic group, or a salt thereof is useful for medicines for preventing and treating various diseases such as arterial schleosis, hepatopathy, cerebrovascular diseases and the like.
