1429218-18-7Relevant articles and documents
Tandem ring-closing metathesis/isomerization reactions for the total synthesis of violacein
Petersen, Mette T.,Nielsen, Thomas E.
supporting information, p. 1986 - 1989 (2013/06/05)
A series of 5-substituted 2-pyrrolidinones was synthesized through a one-pot ruthenium alkylidene-catalyzed tandem RCM/isomerization/nucleophilic addition sequence. The intermediates resulting from RCM/isomerization showed reactivity toward electrophiles in aldol condensation reactions which provided a new entry for the total synthesis of the antileukemic natural product violacein.