142929-46-2

Upstream product

• 142929-45-1 N--3-<(triphenylmethyl)thio>-D-valyl>glycyl>-L-phenylalanyl>-3-mercapto-D-valine 
• 29913-83-5 D-penicillamine methyl ester 
• 106624-70-8 methyl (2S)-2-[[2-(t-butoxycarbonylamino)acetyl]amino]-3-phenylpropanoate 
• 16227-22-8 glycyl-L-phenylalanine methyl ester 
• 135592-14-2 N-Boc-S-trityl-D-Pen-OH 
• 142929-44-0 N--3-<(triphenylmethyl)thio>-D-valyl>glycyl>-L-phenylalanine 
• 142929-43-9 N--3-<(triphenylmethyl)thio>-D-valyl>glycyl>-L-phenylalanine methyl ester 

Downstream Products

• 142929-47-3 methyl 13α-<<2(S)-<<(1,1-dimethylethoxy)carbonyl>amino>-3-(4-hydroxy-2,6-dimethylphenyl)-1-oxopropyl>amino>-3,3,14,14-tetramethyl-6,9,12-trioxo-7β-(phenylmethyl)-1,2-dithia-5,8,11-triazacyclotetradecane-(4R)-4α-carboxylate 
• 142929-39-3 methyl 13α-<<2(S)-amino-3-(4-hydroxyphenyl)-1-oxopropyl>amino>-3,3-14,14-tetramethyl-6,9,12-trioxo-7β-(phenylmethyl)-1,2-dithia-5,8,11-triazacyclotetradecane-(4R)-4α-carboxylate hydrochloride 
• 142929-40-6 methyl 13α-<<2(S)-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-oxopropyl>amino>-3,3-14,14-tetramethyl-6,9,12-trioxo-7β-(phenylmethyl)-1,2-dithia-5,8,11-triazacyclotetradecane-(4R)-4α-carboxylate hydrochloride 
• 749180-44-7 (4S,7S,13S)-13-Amino-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Analogs of the δ opioid receptor selective cyclic peptide [2-D- penicillamine,5-D-penicillamine]-enkephalin: 2',6'-Dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions

In order to develop systemically-active opioid peptides, the δ-selective, opioid pentapeptide [D-Pen2,D-Pen5]-enkephalin (DPDPE) was modified by esterification and by substitution of 2',6'-dimethyltyrosine for tyrosine to yield 4. Co