1429313-63-2

Upstream product

• 960613-96-1 3-bromo-5-chloro-pyrazolo[1,5-a]pyrimidine 
• 1429313-61-0 C₂₄H₂₉BrN₆O₈S 
• 1429313-60-9 C₁₉H₂₁BrN₆O₆S 
• 1429313-59-6 C₁₄H₁₃BrN₆O₄S 
• 92504-03-5 N-(2-aminoethyl)-2-nitrobenzenesulfonamide hydrochloride 

Downstream Products

• 1429313-65-4 C₂₂H₂₁N₇O₆S 
• 1429313-66-5 C₂₂H₁₉N₇O₅S 
• 1429313-64-3 C₂₃H₂₃N₇O₆S 

Relevant academic research and scientific papers

MACROCYCLIC FLT3 KINASE INHIBITORS

The present invention relates to macrocylic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of FLT3 (FMS-Related Tyrosine kinase 3). Moreover, the present invention provides processes for the preparation of the disclosed compounds, as well as methods of using them, for instance as a medicine, in particular for the treatment of cell proliferative disorders, such as cancer.

MACROCYCLIC FLT3 KINASE INHIBITORS

The present invention relates to macrocylic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of FLT3 (FMS-Related Tyrosine kinase 3). Moreover, the present invention provides processes for the preparation of the disclosed compounds, as well as methods of using them, for instance as a medicine, in particular for the treatment of cell proliferative disorders, such as cancer.