1429323-75-0

Upstream product

• 1429323-58-9 C₁₈H₂₆BrN₅O₄ 
• 1429323-57-8 C₁₃H₁₈BrN₅O₂ 
• 1429323-74-9 C₃₁H₄₃N₅O₇ 
• 769968-18-5 tert-butyl 2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)acetate 
• 277331-38-1 tert-butyl 2-(3-bromophenoxy)acetate 
• 1429323-72-7 C₁₄H₂₀BrN₅O₂ 
• 1429323-71-6 C₂₀H₂₃BrN₆O₆S 
• 1429323-70-5 C₁₉H₂₁BrN₆O₆S 
• 1429313-59-6 C₁₄H₁₃BrN₆O₄S 
• 1429323-69-2 C₈H₁₀BrN₅ 
• 591-20-8 3-Bromophenol 
• 960613-96-1 3-bromo-5-chloro-pyrazolo[1,5-a]pyrimidine 

Relevant academic research and scientific papers

MACROCYCLIC LRRK2 KINASE INHIBITORS

The present invention relates to novel macrocylic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of LRRK2 (Leucine-Rich Repeat Kinase 2). Moreover, the present invention provides processes for the preparation of the disclosed compounds, as well as methods of using them, for instance as a medicine or diagnostic agent, in particular for the treatment and/or diagnosis of diseases characterized by LRRK2 kinase activity such as neurological disorders including Parkinson's disease and Alzheimer's disease