142944-49-8

Basic information

• Product Name: 3-Piperidinecarboxylic acid, 2-oxo-1-[3-(4-phenyl-1-piperazinyl)propyl]-, ethyl ester
• CAS NO: 142944-49-8
• Molecular Formula: C21H31N3O3
• Molecular Weight: 373.495
• Mol File: 142944-49-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Piperidinecarboxylic acid, 2-oxo-1-[3-(4-phenyl-1-piperazinyl)propyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Piperidinecarboxylic acid, 2-oxo-1-[3-(4-phenyl-1-piperazinyl)propyl]-, ethyl ester(142944-49-8)
• EPA Substance Registry System: 3-Piperidinecarboxylic acid, 2-oxo-1-[3-(4-phenyl-1-piperazinyl)propyl]-, ethyl ester(142944-49-8)

Safety Data

• Hazardous Substances Data: 142944-49-8(Hazardous Substances Data)

Upstream product

• 10149-21-0 diethyl 2-(3-bromopropane)malonate 
• 20529-19-5 3-(4-phenylpiperazin-1-yl)propan-1-amine 

Downstream Products

• 142944-38-5 2-<3-(4-phenyl-1-piperazinyl)propyl>-1,2,3,4-tetrahydro-β-carbolin-1-one 
• 142944-50-1 3-(Phenyl-hydrazono)-1-[3-(4-phenyl-piperazin-1-yl)-propyl]-piperidin-2-one 

Relevant articles and documents

Structure-activity relationship studies of CNS agents. Part 4: 2-[3-(4-aryl-1-piperazinyl)propyl]-1,2,3,4-tetrahydro-β-carbolin-1-on e derivatives as potential cetnral anti-serotonin agents

Seven derivatives of 1,2,3,4-tetrahydro-β-carbolin-1-one have been prepared. Three of them showed significant central anti-serotonin activity, comparable with that of trazodone or etoperidone. Some structural features were found to be important for the central antiserotonin activity of the investigated class of compounds.