142944-77-2Relevant academic research and scientific papers
CONSTRUCTION OF CHIRAL QUARTERNARY CARBON CENTERS USING 3-SUBSTITUTED 5-TRIMETHYLSILYL-2-CYCLOHEXENONES: SYNTHESIS OF (+)-α-CUPARENONE
Asaoka, Morio,Takenouchi, Kazuya,Takei, Hisashi
, p. 325 - 328 (2007/10/02)
1,4-Addition of Grignard reagents to 3-substituted 5-trimethylsilyl-2-cyclohexenones proceeded in a highly diastereoselective manner.By utilizing the reaction, (+)-α-cuparenone was synthesized starting from enantiomerically pure 3-p-tolylthio-5-(trimethyl
